Phospho-FAK (Tyr576) Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB11862-50, MB11862-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: Q05397

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB

All Applications: WB: 1/500-1/1000

Background: This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Phospho-FAK in A549, U251, C2C12Lysates using Phospho-FAK antibody.

Bioworld Molecular Weight: Calculated MW: 119 kDa; Observed MW: 125 kDa

Specificity: IgG

Alternative Name: PTK2; FAK; FAK1; Focal adhesion kinase 1; FADK 1; Focal adhesion kinase-related nonkinase; FRNK; Protein phosphatase 1 regulatory subunit 71; PPP1R71; Protein-tyrosine kinase 2; p125FAK; pp125FAK

Immunogen: A synthetic phosphopeptide corresponding to residues surrounding Tyr576 of human FAK

Conjugate: Unconjugated

Modification: Phosphorylated