NRX-1532 is a small molecule enhancer of β-catenin:β-TrCP interaction.

Product information

Molecular Weight: 348.28

Formula: C16H11F3N4O2

Smiles: O=C1NC(=CC=C1C(=O)NC1=CC(=CC=C1)C1=CC=NN1)C(F)(F)F

InChiKey: KRFAUNDDLPKBNF-UHFFFAOYSA-N

InChi: InChI=1S/C16H11F3N4O2/c17-16(18,19)13-5-4-11(15(25)22-13)14(24)21-10-3-1-2-9(8-10)12-6-7-20-23-12/h1-8H,(H,20,23)(H,21,24)(H,22,25)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: To be determined

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

1. Simonetta KR, et al. Prospective discovery of small molecule enhancers of an E3 ligase-substrate interaction. Nat Commun. 2019 Mar 29;10(1):1402

Products are for research use only. Not for human use.