NOXA Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB11839-50, MB11839-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: Q13794

Host: Rabbit

Reactivity: Human

Applications: WB

All Applications: WB: 1/500-1/1000

Background: Noxa is a pro-apoptotic Bcl-2 family protein that contains a single Bcl-2 homology (BH3) domain. Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Noxa in Hela, A549, HL-60, U251Lysates using NOXA antibody.

Bioworld Molecular Weight: Calculated MW: 6 kDa; Observed MW: 10 kDa

Specificity: IgG

Alternative Name: APR; ATL-derived; NOXA; Pmaip1; Protein Noxa

Immunogen: A synthetic peptide of human Noxa

Conjugate: Unconjugated

Modification: Unmodified